The man who ran the workshop that turned a dying mercenary into something that could not die, and who never wanted to be called Francis.
Francis Freeman is Ajax, a mutant immune to pain, and the man who made Wade Wilson into Deadpool. Ed Skrein plays him in Deadpool. He runs the Workshop, the place Wade goes to be cured of cancer and where instead he is tortured until the mutation surfaces, and he is disfigured when Wade escapes.
The reader who sent this list described him as the man who made Wade Wilson into Deadpool, which is accurate, and which Wade spends the whole film holding against him along with the name Francis.
Minor spoiler
He kidnaps Vanessa to bring Wade to him, and Wade kills him at the end.