Blade: Trinity

Framed for murder and hunted by the FBI, Blade ends up working with two much younger hunters against the first vampire of all.

David Goyer wrote all three of these and directs this one. It brings in the Nightstalkers, a second generation of hunters with better equipment and worse discipline, and it goes for the biggest possible antagonist by digging up Dracula himself.

It is the weakest received of the three and the end of the run. It also has a detail worth knowing about: one of the two young hunters is played by Ryan Reynolds, twelve years before he made a career out of a different Marvel character with the same line delivery.